Review



blm induction  (Selleck Chemicals)


Bioz Verified Symbol Selleck Chemicals is a verified supplier
Bioz Manufacturer Symbol Selleck Chemicals manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 96
      Buy from Supplier

    Structured Review

    Selleck Chemicals blm induction
    Fig. 2 TH5487 mitigates <t>BLM-induced</t> <t>pulmonary</t> fibrosis and M2 macrophage polarization, which is partly hindered by Mdivi-1. A BLM-administrated mice were treated with TH5487 or co-treated with TH5487 and Mdivi-1. HE staining and Masson staining were performed to observe the histological changes. B The expression level of Collagen I and α-SMA in lung tissues was examined by western blot. C-D Immunofluorescent analysis was used to detect CD206-positive (M2) cells. ***p < 0.001 vs Sham; ###p < 0.001 vs BLM; &p < 0.05, &&&p < 0.001 vs BLM + TH5487
    Blm Induction, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 187 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/blm induction/product/Selleck Chemicals
    Average 96 stars, based on 187 article reviews
    blm induction - by Bioz Stars, 2026-03
    96/100 stars

    Images

    1) Product Images from "Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy."

    Article Title: Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.

    Journal: Molecular medicine (Cambridge, Mass.)

    doi: 10.1186/s10020-024-00843-6

    Fig. 2 TH5487 mitigates BLM-induced pulmonary fibrosis and M2 macrophage polarization, which is partly hindered by Mdivi-1. A BLM-administrated mice were treated with TH5487 or co-treated with TH5487 and Mdivi-1. HE staining and Masson staining were performed to observe the histological changes. B The expression level of Collagen I and α-SMA in lung tissues was examined by western blot. C-D Immunofluorescent analysis was used to detect CD206-positive (M2) cells. ***p < 0.001 vs Sham; ###p < 0.001 vs BLM; &p < 0.05, &&&p < 0.001 vs BLM + TH5487
    Figure Legend Snippet: Fig. 2 TH5487 mitigates BLM-induced pulmonary fibrosis and M2 macrophage polarization, which is partly hindered by Mdivi-1. A BLM-administrated mice were treated with TH5487 or co-treated with TH5487 and Mdivi-1. HE staining and Masson staining were performed to observe the histological changes. B The expression level of Collagen I and α-SMA in lung tissues was examined by western blot. C-D Immunofluorescent analysis was used to detect CD206-positive (M2) cells. ***p < 0.001 vs Sham; ###p < 0.001 vs BLM; &p < 0.05, &&&p < 0.001 vs BLM + TH5487

    Techniques Used: Staining, Expressing, Western Blot



    Similar Products

    blm induction  (Selleck Chemicals)
    96
    Selleck Chemicals blm induction
    Fig. 2 TH5487 mitigates <t>BLM-induced</t> <t>pulmonary</t> fibrosis and M2 macrophage polarization, which is partly hindered by Mdivi-1. A BLM-administrated mice were treated with TH5487 or co-treated with TH5487 and Mdivi-1. HE staining and Masson staining were performed to observe the histological changes. B The expression level of Collagen I and α-SMA in lung tissues was examined by western blot. C-D Immunofluorescent analysis was used to detect CD206-positive (M2) cells. ***p < 0.001 vs Sham; ###p < 0.001 vs BLM; &p < 0.05, &&&p < 0.001 vs BLM + TH5487
    Blm Induction, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/blm induction/product/Selleck Chemicals
    Average 96 stars, based on 1 article reviews
    blm induction - by Bioz Stars, 2026-03
    96/100 stars
    		  Buy from Supplier

    Image Search Results


    Fig. 2 TH5487 mitigates BLM-induced pulmonary fibrosis and M2 macrophage polarization, which is partly hindered by Mdivi-1. A BLM-administrated mice were treated with TH5487 or co-treated with TH5487 and Mdivi-1. HE staining and Masson staining were performed to observe the histological changes. B The expression level of Collagen I and α-SMA in lung tissues was examined by western blot. C-D Immunofluorescent analysis was used to detect CD206-positive (M2) cells. ***p < 0.001 vs Sham; ###p < 0.001 vs BLM; &p < 0.05, &&&p < 0.001 vs BLM + TH5487

    Journal: Molecular medicine (Cambridge, Mass.)

    Article Title: Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.

    doi: 10.1186/s10020-024-00843-6

    Figure Lengend Snippet: Fig. 2 TH5487 mitigates BLM-induced pulmonary fibrosis and M2 macrophage polarization, which is partly hindered by Mdivi-1. A BLM-administrated mice were treated with TH5487 or co-treated with TH5487 and Mdivi-1. HE staining and Masson staining were performed to observe the histological changes. B The expression level of Collagen I and α-SMA in lung tissues was examined by western blot. C-D Immunofluorescent analysis was used to detect CD206-positive (M2) cells. ***p < 0.001 vs Sham; ###p < 0.001 vs BLM; &p < 0.05, &&&p < 0.001 vs BLM + TH5487

    Article Snippet: One day after BLM induction, the pulmonary fibrosis mice were treated intraperitoneally with TH5487 (30 mg/ kg/twice one week; OGG1-specific inhibitor, Selleck) in BLM + TH5487 group, and were treated intraperitoneally with TH5487 and Mitochondrial division inhibitor 1 (Mdivi-1; 10 mg/kg/twice one week; Selleck) in BLM + TH5487 + Mdivi-1 group.

    Techniques: Staining, Expressing, Western Blot